PSMA Antibody

Catalog Number:

21694

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot: Q04609
NCBI Protein: NP_004467.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around aa.738~750 (A-A-E-T-L) derived Human from PSMA.

Purification:

Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Specificity/Sensitivity:

The antibody detects endogenous level of total PSMA protein.

Applications:

WB

Background:

Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4and isoform PSM-5would appear to be physiologically irrelevant. Involved in prostate tumor progression.

 

Qin B  et al. Identification of a LNCaP-specific binding peptide using phage display. Pharm Res 28:2422-34 (2011)

References:

appl_detail:

 Western blotting: 1:500~1:1000

Datasheet PDF