Product Datasheet  
PSMA Antibody  
Catalog Number: 21694  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot: Q04609
    NCBI Protein: NP_004467.1
  • Form of Antibody：  
  • Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C
  • Immunogen：  
  • Peptide sequence around aa.738~750 (A-A-E-T-L) derived Human from PSMA.
  • reactivity：  
  • Hu
  • appl_detail：  

  •  Western blotting: 1:500~1:1000

  • other_names：  
  • FGCP; Folate hydrolase 1; FOLH; FOLH1; GCP2
  • Purification：  
  • Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
  • Specificity：  
  • The antibody detects endogenous level of total PSMA protein.
  • Applications：  
  • WB
  • Background：  

  • Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4and isoform PSM-5would appear to be physiologically irrelevant. Involved in prostate tumor progression.

     

    Qin B  et al. Identification of a LNCaP-specific binding peptide using phage display. Pharm Res 28:2422-34 (2011)




 
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