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Catalog Number: |
49971 |
other_names: | BAF antibody BAF_HUMAN antibody BANF 1 antibody BANF1 antibody Barrier to autointegration factor 1 antibody Barrier to autointegration factor antibody Barrier-to-autointegration factor antibody BCRG 1 |
Amount: |
100μg |
calculated_mw: | 10 kDa |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:O75531 |
Form of Antibody: |
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Storage/Stability: |
|
Immunogen: |
Full length recombinant protein of human BANF1. |
Purification: |
ProA affinity purified |
Specificity/Sensitivity: |
|
Applications: |
WB,ICC,IHC,FC |
Background: |
Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome. |
References: |
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appl_detail: |
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