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BANF1 Antibody

Catalog Number:

49971
other_names: BAF antibody
BAF_HUMAN antibody
BANF 1 antibody
BANF1 antibody
Barrier to autointegration factor 1 antibody
Barrier to autointegration factor antibody
Barrier-to-autointegration factor antibody
BCRG 1

Amount:

100μg
calculated_mw: 10 kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O75531

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Full length recombinant protein of human BANF1.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,ICC,IHC,FC

Background:

Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.

References:

appl_detail:


IHC: 1:50-1:200
ICC: 1:50-1:100

FC: 1:50-1:100

Datasheet PDF

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