Product Datasheet
BANF1 Antibody
Catalog Number: 49971
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O75531
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Full length recombinant protein of human BANF1.
- appl_detail:
IHC: 1:50-1:200
ICC: 1:50-1:100
FC: 1:50-1:100
- other_names:
- BAF antibody
BAF_HUMAN antibody
BANF 1 antibody
BANF1 antibody
Barrier to autointegration factor 1 antibody
Barrier to autointegration factor antibody
Barrier-to-autointegration factor antibody
BCRG 1
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IHC,FC
- Background:
- Barrier-to-autointegration factor (BAF) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BAF compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BAF from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.
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