Carbonic Anhydrase I Antibody

Catalog Number:

49945

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P00915

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein within human Carbonic Anhydrase I aa 1-200.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

Carbonic anhydrases (CAs), also designated carbonate dehydratases or carbonate hydrolyases, form a large family of genes that encode zinc metalloenzymes of great physiologic importance. As catalysts of the reversible hydration of carbon dioxide, these enzymes participate in a variety of biologic processes, including respiration, acid-base balance, bone resorption and calcification as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. Genes in the α-carbonic anhydrase family encode either active carbonic anhydrase isozymes or "acatalytic" (devoid of CO2 hydration activity) carbonic anhydrase-related proteins. Human CA I (CA1) is encoded by the CA1 gene, which maps to a region on chromosome 8 that harbors a cluster of CA genes. CA I localizes to the cytoplasm and research indicates that a severe deficiency of CA I does not result in any obvious hematological or renal consequences.

References:

appl_detail:

WB: 1:500-1:2,000
IHC: 1:50-1:200

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