Product Datasheet
Carbonic Anhydrase I Antibody
Catalog Number: 49945
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P00915
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein within human Carbonic Anhydrase I aa 1-200.
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
- other_names:
- CA 1 antibody
CA I antibody
CA-I antibody
CA1 antibody
CAB antibody
CAH1_HUMAN antibody
CAI antibody
CAN antibody
Car 1 antibody
Car1 antibody
Carbonate dehydratase I antibody<
- Purification:
- ProA affinity purified
- Background:
- Carbonic anhydrases (CAs), also designated carbonate dehydratases or carbonate hydrolyases, form a large family of genes that encode zinc metalloenzymes of great physiologic importance. As catalysts of the reversible hydration of carbon dioxide, these enzymes participate in a variety of biologic processes, including respiration, acid-base balance, bone resorption and calcification as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. Genes in the α-carbonic anhydrase family encode either active carbonic anhydrase isozymes or "acatalytic" (devoid of CO2 hydration activity) carbonic anhydrase-related proteins. Human CA I (CA1) is encoded by the CA1 gene, which maps to a region on chromosome 8 that harbors a cluster of CA genes. CA I localizes to the cytoplasm and research indicates that a severe deficiency of CA I does not result in any obvious hematological or renal consequences.
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