SOCS2 Antibody

Catalog Number:

49910

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O14508

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein within human SOCS2 1-150aa.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,ICC,IF,IP

Background:

SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.

References:

appl_detail:

WB: 1:500-1:2,000

ICC: 1:50-1:200
IP: 1:10-1:50

Datasheet PDF