Product Datasheet
SOCS2 Antibody
Catalog Number: 49910
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O14508
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein within human SOCS2 1-150aa.
- appl_detail:
- WB: 1:500-1:2,000
ICC: 1:50-1:200
IP: 1:10-1:50
- other_names:
- CIS 2 antibody
CIS-2 antibody
CIS2 antibody
Cish 2 antibody
Cish2 antibody
Cytokine inducible SH2 protein 2 antibody
Cytokine-inducible SH2 protein 2 antibody
SOCS 2 antibody
SOCS-2 antibody<
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IF,IP
- Background:
- SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
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