TGF alpha Antibody

Catalog Number:	49822
other_names:	EGF like TGF antibody EGF-like TGF antibody ETGF antibody TFGA antibody TGF A antibody TGF type 1 antibody TGF-alpha antibody Tgfa antibody TGFA_HUMAN antibody Transforming growth fact
Amount:	100μg
calculated_mw:	17 kDa
host_species:	Rabbit
Price:	$319
Swiss-Prot No:	Swiss-Prot#:P01135
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	Recombinant protein
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	WB,ICC,IF,IHC,IP
Background:	Transforming growth factor-α (TGFα) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGFα is 33% homologous at the amino acid level to epidermal growth factor (EGF). TGFα binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor-β. TGFα is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGFα bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy.
References:
appl_detail:	WB: 1:500 IHC: 1:50-1:200 ICC: 1:50-1:200
	Datasheet PDF

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