Product Datasheet  
TGF alpha Antibody  
Catalog Number: 49822  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P01135
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:500
    IHC: 1:50-1:200
    ICC: 1:50-1:200

  • other_names:  
  • EGF like TGF antibody
    EGF-like TGF antibody
    ETGF antibody
    TFGA antibody
    TGF A antibody
    TGF type 1 antibody
    TGF-alpha antibody
    Tgfa antibody
    TGFA_HUMAN antibody
    Transforming growth fact
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB,ICC,IF,IHC,IP
  • Background:  
  • Transforming growth factor-α (TGFα) is an acid- and heat-stable 50 amino acid protein originally found in rodents and humans. TGFα is 33% homologous at the amino acid level to epidermal growth factor (EGF). TGFα binds to the EGF receptor, mediates tyrosine phosphorylation of the receptor and promotes anchorage-independent growth of normal rat fibroblasts in soft agar in the presence of transforming growth factor-β. TGFα is secreted by a variety of transformed cells and tumors, embryonic cells and some normal adult cells. TGFα bioactivity has been found in the urine of cancer patients. It has been suggested that it may act as an autocrine growth factor for the induction or maintenance of malignancy.



 
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