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GCNF Antibody

Catalog Number:

48479
other_names: GCNF 1 antibody
GCNF antibody
GCNF1 antibody
Germ cell nuclear factor antibody
hGCNF antibody
hRTR antibody
NR 61 antibody
NR61 antibody
nr6a1 antibody
NR6A1_HUMAN antibody
Nuclear receptor subfamily 6 group A member 1 antibody
Orphan nuclear receptor NR6A1 antibody
Retinoic acid receptor related testis associated receptor antibody
Retinoid receptor related testis specific receptor antibody
Retinoid receptor-related testis-specific receptor antibody
RTR antibody

Amount:

100μg
calculated_mw: 54 kDa
host_species: Mouse

Price:

$529

Swiss-Prot No:

Swiss-Prot#:Q15406

Form of Antibody:

1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,ICC,IHC,FC

Background:

Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.

References:

appl_detail:

WB: 1:500-1:1,000
IHC: 1:100-1:500
ICC: 1:50-1:200

FC: 1:100-1:200

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