Product Datasheet  
GCNF Antibody  
Catalog Number: 48479  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q15406
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:1,000
    IHC: 1:100-1:500
    ICC: 1:50-1:200

    FC: 1:100-1:200
  • other_names：  
  • GCNF 1 antibody
    GCNF antibody
    GCNF1 antibody
    Germ cell nuclear factor antibody
    hGCNF antibody
    hRTR antibody
    NR 61 antibody
    NR61 antibody
    nr6a1 antibody
    NR6A1_HUMAN antibody
    Nuclear receptor subfamily 6 group A member 1 antibody
    Orphan nuclear receptor NR6A1 antibody
    Retinoic acid receptor related testis associated receptor antibody
    Retinoid receptor related testis specific receptor antibody
    Retinoid receptor-related testis-specific receptor antibody
    RTR antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,ICC,IHC,FC
  • Background：  
  • Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis; northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.



 
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