PINCH Antibody

Catalog Number:

48476

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#:P48059

Form of Antibody:

1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,ICC,FC

Background:

Pinch, also designated particularly interesting new Cys-His protein or NY-REN-48, is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is a major part of the growth factor and integrin signaling pathway. Pinch is involved in cell differentiation, proliferation and survival by acting as an effector of integrin and growth factor signaling. It is a cytoplasmic protein expressed in most tissues and consists of five LIM domains, a nuclear localization signal and a nuclear export signal. The PINCH-1/ILK complex is regulated by a PINCH-1 related protein PINCH-2, which also forms a complex with ILK.

References:

appl_detail:

WB: 1:500-1:1,000

ICC: 1:100-1:500

FC: 1:100-1:200

Datasheet PDF