Product Datasheet  
PINCH Antibody  
Catalog Number: 48476  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P48059
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:1,000

    ICC: 1:100-1:500

    FC: 1:100-1:200
  • other_names：  
  • 2310016J22Rik antibody
    4921524A02Rik antibody
    AI507642 antibody
    AU021743 antibody
    AW551584 antibody
    C430041B13Rik antibody
    LIM and senescent cell antigen like domains 1 antibody
    LIM and senescent cell antigen-like-containing domain protein 1 antibody
    LIM zinc finger domain containing 1 antibody
    LIM-type zinc finger domains 1 antibody
    Lims1 antibody
    LIMS1_HUMAN antibody
    Lims1l antibody
    Particularly interesting new Cys His protein 1 antibody
    Particularly interesting new Cys His protein antibody
    Particularly interesting new Cys-His protein 1 antibody
    PINCH 1 antibody
    PINCH antibody
    PINCH-1 antibody
    PINCH1 antibody
    Renal carcinoma antigen NY REN 48 antibody
    Renal carcinoma antigen NY-REN-48 antibody
    senescent cell antigen antibody
    wu:fc32c03 antibody
    zgc:112533 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,ICC,FC
  • Background：  
  • Pinch, also designated particularly interesting new Cys-His protein or NY-REN-48, is a focal adhesion protein that is a component of the ILK-PINCH complex. This complex is a major part of the growth factor and integrin signaling pathway. Pinch is involved in cell differentiation, proliferation and survival by acting as an effector of integrin and growth factor signaling. It is a cytoplasmic protein expressed in most tissues and consists of five LIM domains, a nuclear localization signal and a nuclear export signal. The PINCH-1/ILK complex is regulated by a PINCH-1 related protein PINCH-2, which also forms a complex with ILK.



 
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