THAP11 Antibody

Catalog Number:

48466

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#:Q96EK4

Form of Antibody:

1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,ICC,IHC,FC

Background:

Members of the THAP (thanatos-associated protein) family of proteins contain a well conserved DNA-binding domain known as the THAP-type zinc finger motif. Proteins containing the THAP-type zinc finger motif are commonly involved in transcriptional regulation, cell-cycle control, apoptosis and chromatin modification. The THAP-type zinc finger domain is suggested to have similarities with the site-specific DNA-binding domain (DBD) of Drosophila P element transposase. THAP11 (THAP domain containing 11), also known as HRIHFB2206, is a 314 amino acid protein that belongs to the THAP11 family and contains one THAP-type zinc finger. Localizing to the nucleus and cytoplasm, THAP11 may act as a transcriptional repressor, playing a role in embryogenesis and pluripotency of embryonic stem cells by recruiting epigenetic modifiers. THAP11 interacts with HCF1 via a coiled coil domain.

References:

appl_detail:

WB: 1:500
IHC: 1:50-1:200
ICC: 1:100-1:500

FC: 1:100-1:200

Datasheet PDF