Product Datasheet
THAP11 Antibody
Catalog Number: 48466
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q96EK4
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500
IHC: 1:50-1:200
ICC: 1:100-1:500
FC: 1:100-1:200
- other_names:
- CTG B43a antibody
CTG B45d antibody
HRIHFB2206 antibody
RONIN antibody
THA11_HUMAN antibody
THAP 11 antibody
THAP domain containing 11 antibody
THAP domain-containing protein 11 antibody
Thap11 antibody
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IHC,FC
- Background:
- Members of the THAP (thanatos-associated protein) family of proteins contain a well conserved DNA-binding domain known as the THAP-type zinc finger motif. Proteins containing the THAP-type zinc finger motif are commonly involved in transcriptional regulation, cell-cycle control, apoptosis and chromatin modification. The THAP-type zinc finger domain is suggested to have similarities with the site-specific DNA-binding domain (DBD) of Drosophila P element transposase. THAP11 (THAP domain containing 11), also known as HRIHFB2206, is a 314 amino acid protein that belongs to the THAP11 family and contains one THAP-type zinc finger. Localizing to the nucleus and cytoplasm, THAP11 may act as a transcriptional repressor, playing a role in embryogenesis and pluripotency of embryonic stem cells by recruiting epigenetic modifiers. THAP11 interacts with HCF1 via a coiled coil domain.
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