Serum Amyloid A (SAA) Antibody

Catalog Number:

48336

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot:P02735
Gene ID:6288

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Highly purified recombinant SAA of human origin

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, IP

Background:

The serum Amyloid A (SAA) family of proteins is encoded by muliple genes, which display allelic variation and a high degree of homology in mammals. The four members of the SAA gene family are clustered on human chromo- some 11p15.1. Three SAA genes are differentially expressed and encode small apolipoproteins. SAA1 and SAA2 encode the acute phase SAAs (A-SAAs) and SAA4 encodes the constitutively expressed SAA (C-SAA). A fourth locus, SAA3, is a pseudogene that contains two C/EBP-binding sites and a third site, which interacts with SAA3 enhancer factor . Human SAA proteins are a group of apolipoproteins found predominantly in the high-density lipoprotein (HDL) fraction of plasma. SAA is a major acute-phase protein and precursor to Amyloid A protein, which is the major constituent of the fibril deposits of reactive amyloidosis. SAA is secreted in large amounts by the liver during microbial infections or inflammatory diseases.

References:

appl_detail:

WB: 1:100-1:1,000


IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)

Datasheet PDF