Product Datasheet
Serum Amyloid A (SAA) Antibody
Catalog Number: 48336
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:P02735
Gene ID:6288
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Highly purified recombinant SAA of human origin
- appl_detail:
- WB: 1:100-1:1,000
IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
- other_names:
- Amyloid fibril protein AA antibody Amyloid fibrils antibody Amyloid protein A antibody Fibrils antibody MGC111216 antibody OC antibody PIG 4 antibody PIG4 antibody SAA 1 antibody SAA 2 antibody SAA antibody SAA_HUMAN antibody SAA1 antibody SAA2 antibody Serum amyloid A protein precursor antibody Serum amyloid A1 isoform 1 antibody Serum amyloid A1 isoform 2 antibody Serum amyloid protein A(4-101) antibody TP53I4 antibody Tumor protein p53 inducible protein 4 antibody
- Purification:
- ProA affinity purified
- Background:
- The serum Amyloid A (SAA) family of proteins is encoded by muliple genes, which display allelic variation and a high degree of homology in mammals. The four members of the SAA gene family are clustered on human chromo- some 11p15.1. Three SAA genes are differentially expressed and encode small apolipoproteins. SAA1 and SAA2 encode the acute phase SAAs (A-SAAs) and SAA4 encodes the constitutively expressed SAA (C-SAA). A fourth locus, SAA3, is a pseudogene that contains two C/EBP-binding sites and a third site, which interacts with SAA3 enhancer factor . Human SAA proteins are a group of apolipoproteins found predominantly in the high-density lipoprotein (HDL) fraction of plasma. SAA is a major acute-phase protein and precursor to Amyloid A protein, which is the major constituent of the fibril deposits of reactive amyloidosis. SAA is secreted in large amounts by the liver during microbial infections or inflammatory diseases.
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