Human IgG4 Antibody

Catalog Number:

48305

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#:P01861

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

IgG4 of human origin.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

Background:

The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.

References:

appl_detail:

Datasheet PDF