Product Datasheet  
Human IgG4 Antibody  
Catalog Number: 48305  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P01861
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • IgG4 of human origin.
  • reactivity:  
  • Hu
  • appl_detail:  




  • other_names:  
  • Ig gamma 4 chain C region antibody
    IGHG4 antibody
    immunoglobulin heavy chain constant region gamma 4 antibody
    Immunoglobulin heavy constant gamma 4 (G4m marker) antibody
    MGC117419 antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • Background:  
  • The regions of relatively constant sequence beyond the variable regions of immunoglobulins are termed constant regions (C regions) and are present in both the heavy and light chains. With very few exceptions, the sites of attachment for carbohydrates on immunoglobulins are located in these C regions. These regions also function to hold the variable regions together by using the disulfide bond between them. The C regions facilitate interaction with the antigen by increasing the maximum rotation of the immunoglobulin arms. Several studies have shown that a large population of patients with recurrent respiratory tract infection have low IgG4 concentrations.



 
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