CD141 Antibody

Catalog Number:

48281

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#:P07204

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

peptide

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, IP, IHC, FCM

Background:

Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.

References:

appl_detail:

WB: 1:500-1:1000
IHC: 1:50-500

IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
FC: 1 μg per 1 x 106 cells

Datasheet PDF