Product Datasheet  
CD141 Antibody  
Catalog Number: 48281  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P07204
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • peptide
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:500-1:1000
    IHC: 1:50-500

    IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
    FC: 1 μg per 1 x 106 cells
  • other_names:  
  • AHUS 6 antibody
    AHUS6 antibody
    BDCA 3 antibody
    BDCA3 antibody
    CD 141 antibody
    CD141 antibody
    CD141 antigen antibody
    Fetomodulin antibody
    Thbd antibody
    THPH12 antibody
    THRM antibody
    Thrombomodulin antibody
    TM antibody
    TRBM_HUMAN antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, IP, IHC, FCM
  • Background:  
  • Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.



 
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