CCDC111 Antibody

Catalog Number:

48105

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#:Q96LW4

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

recombinant protein

Purification:

ProG affinity purified

Specificity/Sensitivity:

Applications:

ICC, IHC

Background:

DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. PRIMPOL shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. It is involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. PRIMPOL is required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. PRIMPOL has non-overlapping function with POLH.

References:

appl_detail:

IHC: 1:200
ICC: 1:100-1:200

Datasheet PDF