Product Datasheet  
CCDC111 Antibody  
Catalog Number: 48105  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q96LW4
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  

  • IHC: 1:200
    ICC: 1:100-1:200

  • other_names：  
  • CC111_HUMAN antibody
    CCDC111 antibody
    Coiled coil domain containing 111 antibody
    Coiled-coil domain-containing protein 111 antibody
    DNA-directed primase/polymerase protein antibody
    MYP22 antibody
    Primase and polymerase (DNA directed) antibody
    PRIMPOL antibody
  • Purification：  
  • ProG affinity purified
  • Specificity：  
  • Applications：  
  • ICC, IHC
  • Background：  
  • DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. PRIMPOL shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. It is involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. PRIMPOL is required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. PRIMPOL has non-overlapping function with POLH.



 
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