14-3-3 b/a Antibody

Catalog Number:	48054
other_names:	14 3 3 alpha antibody 14 3 3 protein beta/alpha antibody 14-3-3 protein beta/alpha antibody 1433B_HUMAN antibody Brain protein 14 3 3 beta isoform antibody GW128 antibody HS 1 antibody KCIP-1 antibody KCIP1 antibody N-terminally processed antibody Protein 1054 antibody Protein kinase C inhibitor protein 1 antibody YWHAA antibody YWHAB antibody
Amount:	100μg
calculated_mw:	28 kDa
host_species:	Mouse
Price:	$529
Swiss-Prot No:	Swiss-Prot#:P31946
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	peptide
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	WB, ICC, IHC
Background:	The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints. The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol. The 14-3-3 proteins are also Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. They bind to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
References:
appl_detail:	WB: 1:1,000-1:2,000 IHC: 1:200 ICC: 1:100
	Datasheet PDF

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