Product Datasheet
14-3-3 b/a Antibody
Catalog Number: 48054
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P31946
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- reactivity:
- Hu, Ms, Rt, zebrafish
- appl_detail:
- WB: 1:1,000-1:2,000
IHC: 1:200
ICC: 1:100
- other_names:
- 14 3 3 alpha antibody
14 3 3 protein beta/alpha antibody
14-3-3 protein beta/alpha antibody
1433B_HUMAN antibody
Brain protein 14 3 3 beta isoform antibody
GW128 antibody
HS 1 antibody
KCIP-1 antibody
KCIP1 antibody
N-terminally processed antibody
Protein 1054 antibody
Protein kinase C inhibitor protein 1 antibody
YWHAA antibody
YWHAB antibody
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC, IHC
- Background:
- The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints. The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol. The 14-3-3 proteins are also Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. They bind to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
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