Product Datasheet  
14-3-3 b/a Antibody  
Catalog Number: 48054  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P31946
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • peptide
  • reactivity:  
  • Hu, Ms, Rt, zebrafish
  • appl_detail:  
  • WB: 1:1,000-1:2,000
    IHC: 1:200
    ICC: 1:100

  • other_names:  
  • 14 3 3 alpha antibody
    14 3 3 protein beta/alpha antibody
    14-3-3 protein beta/alpha antibody
    1433B_HUMAN antibody
    Brain protein 14 3 3 beta isoform antibody
    GW128 antibody
    HS 1 antibody
    KCIP-1 antibody
    KCIP1 antibody
    N-terminally processed antibody
    Protein 1054 antibody
    Protein kinase C inhibitor protein 1 antibody
    YWHAA antibody
    YWHAB antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC, IHC
  • Background:  
  • The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints. The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol. The 14-3-3 proteins are also Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. They bind to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.



 
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