Interleukin-1 receptor antagonist Polyclonal Antibody

Catalog Number:

42463

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P18510

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Interleukin-1 receptor antagonist protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Interleukin-1 receptor antagonist polyclonal antibody.

Applications:

WB IHC

Background:

Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.

References:

[1] "Purification, cloning, expression and biological characterization of an interleukin-1 receptor antagonist protein."Carter D.B., Deibel M.R. Jr., Dunn C.J., Tomich C.S.C., Laborde A.L., Slightom J.L., Berger A.E., Bienkowski M.J., Sun F.F.,

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF