Product Datasheet
Interleukin-1 receptor antagonist Polyclonal Antibody
Catalog Number: 42463
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P18510
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant human Interleukin-1 receptor antagonist protein
- appl_detail:
- Western blotting: 1:500 - 1:1000
- other_names:
- ICIL-1RA, IL1 inhibitor, INN=Anakinra IL1RN, IL1F3, IL1RA
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total Interleukin-1 receptor antagonist polyclonal antibody.
- Background:
- Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
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