Ki 67 Mouse Monoclonal Antibody

Catalog Number:

38019

Amount:

100μg

Price:

$369

Swiss-Prot No:

Swiss-Prot#:P46013

Form of Antibody:

Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Purification:

Affinity purification using immunogen.

Specificity/Sensitivity:

The Ki 67 Mouse Monoclonal antibody detects endogenous Ki 67 protein.s

Applications:

IHC,IF

Background:

KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis. The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0).

References:

appl_detail:

IHC dilution: 1:200

IF dilution:1:50-200

Datasheet PDF