Product Datasheet
Ki 67 Mouse Monoclonal Antibody
Catalog Number: 38019
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P46013
- Form of Antibody:
- Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- appl_detail:
- IHC dilution: 1:200
IF dilution:1:50-200
- other_names:
- antigen identified by monoclonal antibody Ki-67; Antigen KI-67; KI67; KIA; MKI67
- Purification:
- Affinity purification using immunogen.
- Specificity:
- The Ki 67 Mouse Monoclonal antibody detects endogenous Ki 67 protein.s
- Background:
- KI-67 is a nuclear protein that is associated with and may be necessary for cellular proliferation. Furthermore it is associated with ribosomal RNA transcription. Inactivation of antigen KI-67 leads to inhibition of ribosomal RNA synthesis. The Ki-67 protein (also known as MKI67) is a cellular marker for proliferation. It is strictly associated with cell proliferation. During interphase, the Ki-67 antigen can be exclusively detected within the cell nucleus, whereas in mitosis most of the protein is relocated to the surface of the chromosomes. Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0).
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