1-832-868-1888
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Catalog Number: |
38003 |
other_names: | CD20; CK-20; CK20; cytokeratin 20; Cytokeratin-20; K1C20; K20 |
Amount: |
100μg |
calculated_mw: | |
host_species: | Mouse |
Price: |
$369 |
Swiss-Prot No: |
Swiss-Prot#:P35900 |
Form of Antibody: |
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage/Stability: |
|
Immunogen: |
|
Purification: |
Affinity purification using immunogen. |
Specificity/Sensitivity: |
The CD20 antibody detects endogenous CD20 proteins. |
Applications: |
IHC |
Background: |
CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca2+ channel subunit. |
References: |
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appl_detail: |
IHC dilution: 1:200 |
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