Product Datasheet
CD20 Mouse Monoclonal Antibody
Catalog Number: 38003
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P35900
- Form of Antibody:
- Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- appl_detail:
- IHC dilution: 1:200
- other_names:
- CD20; CK-20; CK20; cytokeratin 20; Cytokeratin-20; K1C20; K20
- Purification:
- Affinity purification using immunogen.
- Specificity:
- The CD20 antibody detects endogenous CD20 proteins.
- Background:
- CD20 is a non glycosylated protein with a molecular weight of 35 or 37 kDa depending on the degree of phosphorylation. Although not a member of the tetraspanin superfamily of cell surface receptors, it crosses the cell membrane four times. The CD20 antigen is present on human pre B lymphocytes and on B lymphocytes at all stages of maturation, except on plasma cells. Low level expression of the CD20 antigen has been detected on normal T lymphocytes. The CD20 molecule is involved in regulation of B cell differentiation, presumably via its reported function as a Ca2+ channel subunit.
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