1-832-868-1888
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Catalog Number: |
38072 |
other_names: | ATP-dependent RNA helicase eIF4A-1; DDX2A; EIF-4A; eIF-4A-I; EIF4A; eIF4A-I; EIF4A1; Eukaryotic initiation factor 4A-I |
Amount: |
100μg |
calculated_mw: | |
host_species: | Mouse |
Price: |
$369 |
Swiss-Prot No: |
Swiss-Prot#:P60842 |
Form of Antibody: |
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Storage/Stability: |
|
Immunogen: |
|
Purification: |
Affinity purification using immunogen. |
Specificity/Sensitivity: |
Antibody detects endogenous eIF4A1 protein. |
Applications: |
WB,IHC,IF |
Background: |
The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA ¨C this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression. |
References: |
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appl_detail: |
WB dilution: 1:1000~1:3000 |
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