Product Datasheet  
eIF4A1 Mouse Monoclonal Antibody  
Catalog Number: 38072  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P60842
  • Form of Antibody:  
  • Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • reactivity:  
  • Hu Rt Ms
  • appl_detail:  
  • WB dilution: 1:1000~1:3000
    IHC dilution:1:50-300
    IF dilution:1:100-200
  • other_names:  
  • ATP-dependent RNA helicase eIF4A-1; DDX2A; EIF-4A; eIF-4A-I; EIF4A; eIF4A-I; EIF4A1; Eukaryotic initiation factor 4A-I
  • Purification:  
  • Affinity purification using immunogen.
  • Specificity:  
  • Antibody detects endogenous eIF4A1 protein.
  • Applications:  
  • WB,IHC,IF
  • Background:  
  • The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA ¨C this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression.



 
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