Product Datasheet
eIF4A1 Mouse Monoclonal Antibody
Catalog Number: 38072
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P60842
- Form of Antibody:
- Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- appl_detail:
- WB dilution: 1:1000~1:3000
IHC dilution:1:50-300
IF dilution:1:100-200
- other_names:
- ATP-dependent RNA helicase eIF4A-1; DDX2A; EIF-4A; eIF-4A-I; EIF4A; eIF4A-I; EIF4A1; Eukaryotic initiation factor 4A-I
- Purification:
- Affinity purification using immunogen.
- Specificity:
- Antibody detects endogenous eIF4A1 protein.
- Background:
- The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. Eukaryotic initiation factor (eIF) complex 2 forms a ternary complex with GTP and the initiator Met-tRNA ¨C this process is regulated by guanine nucleotide exchange and phosphorylation and serves as the main regulatory element of the bottleneck of protein expression.
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