PP1C Monoclonal Antibody

Catalog Number:

27177

Amount:

100μg

Price:

$369

Swiss-Prot No:

Uniprot: P36873

Gene ID: 5501

Form of Antibody:

Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.2% sodium azide,0.1mg/mlBSA and 50% glycerol.

Storage/Stability:

Immunogen:

Purified recombinant human PPP1CC protein fragments expressed in E.coli.

Purification:

Affinity purified

Specificity/Sensitivity:

This antibody detects endogenous levels of PPP1CC and does not cross-react with related proteins.

Applications:

WB

Background:

 Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.Protein phosphatase 1(PP1)is essential for cell division,and participates in the regulation of glycogen metabolism,muscle contractility and protein synthesis.Dephosphorylates RPS6KB1.Involved in regulation of ionic conductances and long-term synaptic plasticity.May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.Component of the PTW/PP1 phosphatase complex,which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.

References:

appl_detail:

 Western blotting: 1:500

Datasheet PDF