Product Datasheet  
PP1C Monoclonal Antibody  
Catalog Number: 27177  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Uniprot: P36873

    Gene ID: 5501

  • Form of Antibody：  
  • Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine(pH 7.4,150 mM NaCl)with 0.2% sodium azide,0.1mg/mlBSA and 50% glycerol.
  • Storage：  
  • store at -20˚C
  • Immunogen：  
  • Purified recombinant human PPP1CC protein fragments expressed in E.coli.
  • reactivity：  
  • Hu
  • appl_detail：  

  •  Western blotting: 1:500

  • other_names：  
  • EC 3.1.3.16; PP 1G; PP-1G; PP1G; PP1G_HUMAN; PP1gamma; PPP 1G; PPP1CC; PPP1CC protein; PPP1G; Protein phosphatase 1 catalytic subunit gamma isoform; Protein phosphatase 1C catalytic subunit; Protein phosphatase 1C subunit
  • Purification：  
  • Affinity purified
  • Specificity：  
  • This antibody detects endogenous levels of PPP1CC and does not cross-react with related proteins.
  • Applications：  
  • WB
  • Background：  

  •  Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets.Protein phosphatase 1(PP1)is essential for cell division,and participates in the regulation of glycogen metabolism,muscle contractility and protein synthesis.Dephosphorylates RPS6KB1.Involved in regulation of ionic conductances and long-term synaptic plasticity.May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II.Component of the PTW/PP1 phosphatase complex,which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.




 
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