CD54(ICAM-1) Monoclonal Antibody

Catalog Number:	27176
other_names:	BB 2; BB2; CD 54; CD_antigen=CD54; CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM 1; ICAM-1; ICAM1; ICAM1_HUMAN; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA 2; MALA2; MyD 10; MyD10; P3.58
Amount:	100μg
calculated_mw:
host_species:	Mouse
Price:	$369
Swiss-Prot No:	Uniprot: P05362 Gene ID: 3383
Form of Antibody:	Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
Storage/Stability:
Immunogen:	Purified recombinant human ICAM1(C-terminus) protein fragments expressed in E.coli.
Purification:	Affinity purified
Specificity/Sensitivity:	This antibody detects endogenous levels of ICAM1(C-terminus) and does not cross-react with related proteins.
Applications:	WB ICC
Background:	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
References:
appl_detail:	Western blotting: 1:1000 Immunocytochemistry: 1:200
	Datasheet PDF

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