Product Datasheet
CD54(ICAM-1) Monoclonal Antibody
Catalog Number: 27176
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Uniprot: P05362
Gene ID: 3383
- Form of Antibody:
- Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
- Immunogen:
- Purified recombinant human ICAM1(C-terminus) protein fragments expressed in E.coli.
- other_names:
- BB 2; BB2; CD 54; CD_antigen=CD54; CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM 1; ICAM-1; ICAM1; ICAM1_HUMAN; Intercellular adhesion molecule 1; Major group rhinovirus receptor; MALA 2; MALA2; MyD 10; MyD10; P3.58
- Purification:
- Affinity purified
- Specificity:
- This antibody detects endogenous levels of ICAM1(C-terminus) and does not cross-react with related proteins.
- Background:
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
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