STARD5 Antibody

Catalog Number:

40375

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NSY2
Gene Accssion:NP_871629

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to residues near the N terminal of human StAR-related lipid transfer (START) domain containing 5

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total STARD5 protein.

Applications:

WB IHC

Background:

Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry:1:40-1:150

Datasheet PDF