SRGAP2 Antibody

Catalog Number:

40373

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O75044
Gene Accssion:NP_056141

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide corresponding to a region derived from internal residues of human SLIT-ROBO Rho GTPase activating protein 2

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SRGAP2 protein.

Applications:

IHC

Background:

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes.?

References:

appl_detail:

Immunohistochemistry:1:25-1:100

Datasheet PDF