Product Datasheet
SRGAP2 Antibody
Catalog Number: 40373
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O75044
Gene Accssion:NP_056141
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Synthetic peptide corresponding to a region derived from internal residues of human SLIT-ROBO Rho GTPase activating protein 2
- appl_detail:
-
Immunohistochemistry:1:25-1:100
- other_names:
- FNBP2; SRGAP3; SRGAP2A; ARHGAP34
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total SRGAP2 protein.
- Background:
- This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes.?
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