TPX2 Antibody

Catalog Number:

40347

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9ULW0
Gene Accssion:BC004136

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human TPX2, microtubule-associated

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TPX2 protein.

Applications:

WB IHC

Background:

Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry:1:30-1:150

Datasheet PDF