Product Datasheet
TPX2 Antibody
Catalog Number: 40347
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9ULW0
Gene Accssion:BC004136
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein of human TPX2, microtubule-associated
- appl_detail:
- Western blotting: 1:500-1:2000
Immunohistochemistry:1:30-1:150
- other_names:
- DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total TPX2 protein.
- Background:
- Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
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