RRAGA Antibody

Catalog Number:

40326

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q7L523
Gene Accssion:BC006433

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RRAGA protein.

Applications:

WB IHC

Background:

Ras-related GTP-binding protein A?is a?protein?that in humans is encoded by the?RRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry:1:25-1:100

Datasheet PDF