Product Datasheet  
RRAGA Antibody  
Catalog Number: 40326  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q7L523
    Gene Accssion:BC006433
  • Form of Antibody：  
  • Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Full length fusion protein
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • Western blotting: 1:500-1:2000
    Immunohistochemistry:1:25-1:100
  • other_names：  
  • FIP1; RAGA; FIP-1
  • Purification：  
  • Antigen affinity purification.
  • Specificity：  
  • The antibody detects endogenous levels of total RRAGA protein.
  • Applications：  
  • WB IHC
  • Background：  
  • Ras-related GTP-binding protein A?is a?protein?that in humans is encoded by the?RRAGAgene. Guanine nucleotide-binding protein forming heterodimeric Rag complexes required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids. Involved in the RCC1/Ran-GTPase pathway. May play a direct role in a TNF-alpha signaling pathway leading to induction of cell death.



 
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