RNF14 Antibody

Catalog Number:

40324

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9UBS8
Gene Accssion:BC126185

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human ring finger protein 14

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RNF14 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry:1:25-1:100

Datasheet PDF