Product Datasheet
RNF14 Antibody
Catalog Number: 40324
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q9UBS8
Gene Accssion:BC126185
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human ring finger protein 14
- appl_detail:
- Western blotting: 1:200-1:1000
Immunohistochemistry:1:25-1:100
- other_names:
- ARA54; HFB30; TRIAD2; HRIHFB2038
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total RNF14 protein.
- Background:
- The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins.?
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