RASAL1 Antibody

Catalog Number:

40316

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O95294
Gene Accssion:BC014420

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein corresponding to residues near the N terminal of human RAS protein activator like 1 (GAP1 like)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total RASAL1 protein.

Applications:

WB IHC

Background:

The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation.?

References:

appl_detail:

Western blotting: 1:200-1:1000
Immunohistochemistry: 1:100-1:200

Datasheet PDF