Product Datasheet
RASAL1 Antibody
Catalog Number: 40316
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:O95294
Gene Accssion:BC014420
- Form of Antibody:
- Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
- Immunogen:
- Fusion protein corresponding to residues near the N terminal of human RAS protein activator like 1 (GAP1 like)
- Purification:
- Antigen affinity purification.
- Specificity:
- The antibody detects endogenous levels of total RASAL1 protein.
- Background:
The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation.?
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