VPS26A Antibody

Catalog Number:

40295

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:O75436
Gene Accssion:NP_004887

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human vacuolar protein sorting 26 homolog A (S. pombe)

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total VPS26A protein.

Applications:

WB IHC

Background:

This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

References:

appl_detail:

Western blotting: 1:500-1:2000
Immunohistochemistry:1:30-1:150

Datasheet PDF